A weight-loss intervention in primary care may lead to type 2 diabetes remission, suggests a Lancet study.
Nearly 50 U.K. primary care practices were randomized to deliver either a weight loss intervention or best-practice care (control) to 300 non-insulin-dependent adults with type 2 diabetes (diagnosed within past 6 years) and a BMI of 27–45. For the intervention, patients discontinued antidiabetic and antihypertensive drugs and followed a low-calorie formula diet (825–853 calories daily) for 3 months. This was followed by reintroduction of food and physical activity strategies for 2–8 weeks, and then weight loss maintenance.
At 12 months, 24% of participants in the intervention group lost 15 kg or more; none in the control group did. Diabetes remission was also higher with the intervention (46% vs. 4%).
A commentator says that the study “indicates that the time of diabetes diagnosis is the best point to start weight reduction and lifestyle changes because motivation of a patient is usually high and can be enhanced by the professional health-care providers.”
By Kelly Young